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Vasculogenic Mimicry of HT1080 Tumour Cells In Vivo: Critical Role of HIF-1α-Neuropilin-1 Axis

HT1080 - a human fibrosarcoma-derived cell line – forms aggressive angiogenic tumours in immuno-compromised mice. In spite of its extensive use as a model of tumour angiogenesis, the molecular event(s) initiating the angiogenic program in these cells are not known. Since hypoxia stimulates tumour an...

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Detalles Bibliográficos
Autores principales: Misra, Roli M., Bajaj, Manmohan S., Kale, Vaijayanti P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504006/
https://www.ncbi.nlm.nih.gov/pubmed/23185562
http://dx.doi.org/10.1371/journal.pone.0050153