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High CCR5 Density on Central Memory CD4(+) T Cells in Acute HIV-1 Infection Is Mostly Associated with Rapid Disease Progression

CD4+ central memory T cells play a critical role in the pathogenesis of simian immunodeficiency virus disease, and the CCR5 density on the surface of CD4 T cells is an important factor in human immunodeficiency virus (HIV)-1 disease progression. We hypothesized that quantifying central memory cells...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Jiao, Yan-mei, Wang, Rui, Ji, Yun-xia, Zhang, Hong-wei, Zhang, Yong-hong, Chen, De-xi, Zhang, Tong, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504013/
https://www.ncbi.nlm.nih.gov/pubmed/23185351
http://dx.doi.org/10.1371/journal.pone.0049526