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Association of Germline Variation in CCNE1 and CDK2 with Breast Cancer Risk, Progression and Survival among Chinese Han Women

BACKGROUND: Somatic alterations of cyclin-dependent kinase 2 (CDK2)-cyclin E complex have been shown to contribute to breast cancer (BC) development and progression. This study aimed to explore the effects of single nucleotide polymorphisms (SNPs) in CDK2 and CCNE1 (a gene encoding G1/S specific cyc...

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Detalles Bibliográficos
Autores principales: Han, Ji-Yuan, Wang, Hui, Xie, Yun-Tao, Li, Yan, Zheng, Li-Yuan, Ruan, Yuan, Song, Ai-Ping, Tian, Xin-Xia, Fang, Wei-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504019/
https://www.ncbi.nlm.nih.gov/pubmed/23185313
http://dx.doi.org/10.1371/journal.pone.0049296