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Mind the Gap: Upgrading Genomes with Pacific Biosciences RS Long-Read Sequencing Technology

Many genomes have been sequenced to high-quality draft status using Sanger capillary electrophoresis and/or newer short-read sequence data and whole genome assembly techniques. However, even the best draft genomes contain gaps and other imperfections due to limitations in the input data and the tech...

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Detalles Bibliográficos
Autores principales: English, Adam C., Richards, Stephen, Han, Yi, Wang, Min, Vee, Vanesa, Qu, Jiaxin, Qin, Xiang, Muzny, Donna M., Reid, Jeffrey G., Worley, Kim C., Gibbs, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504050/
https://www.ncbi.nlm.nih.gov/pubmed/23185243
http://dx.doi.org/10.1371/journal.pone.0047768