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Mind the Gap: Upgrading Genomes with Pacific Biosciences RS Long-Read Sequencing Technology
Many genomes have been sequenced to high-quality draft status using Sanger capillary electrophoresis and/or newer short-read sequence data and whole genome assembly techniques. However, even the best draft genomes contain gaps and other imperfections due to limitations in the input data and the tech...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504050/ https://www.ncbi.nlm.nih.gov/pubmed/23185243 http://dx.doi.org/10.1371/journal.pone.0047768 |