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Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

Inhibition of VEGF signalling effectively suppresses localized tumour growth but accelerates tumour invasiveness and micrometastasis by unknown mechanisms. To study the dynamic and reciprocal interactions between tumour cells and their microenvironment during these processes, we established a xenogr...

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Detalles Bibliográficos
Autores principales: He, Shuning, Lamers, Gerda EM, Beenakker, Jan-Willem M, Cui, Chao, Ghotra, Veerander PS, Danen, Erik HJ, Meijer, Annemarie H, Spaink, Herman P, Snaar-Jagalska, B Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504093/
https://www.ncbi.nlm.nih.gov/pubmed/22374800
http://dx.doi.org/10.1002/path.4013