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A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

Sirtuins are protein deacetylases regulating metabolism, stress responses, and aging processes, and they were suggested to mediate the lifespan extending effect of a low calorie diet. Sirtuin activation by the polyphenol resveratrol can mimic such lifespan extending effects and alleviate metabolic d...

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Detalles Bibliográficos
Autores principales: Gertz, Melanie, Nguyen, Giang Thi Tuyet, Fischer, Frank, Suenkel, Benjamin, Schlicker, Christine, Fränzel, Benjamin, Tomaschewski, Jana, Aladini, Firouzeh, Becker, Christian, Wolters, Dirk, Steegborn, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504108/
https://www.ncbi.nlm.nih.gov/pubmed/23185430
http://dx.doi.org/10.1371/journal.pone.0049761