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A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol
Sirtuins are protein deacetylases regulating metabolism, stress responses, and aging processes, and they were suggested to mediate the lifespan extending effect of a low calorie diet. Sirtuin activation by the polyphenol resveratrol can mimic such lifespan extending effects and alleviate metabolic d...
Autores principales: | Gertz, Melanie, Nguyen, Giang Thi Tuyet, Fischer, Frank, Suenkel, Benjamin, Schlicker, Christine, Fränzel, Benjamin, Tomaschewski, Jana, Aladini, Firouzeh, Becker, Christian, Wolters, Dirk, Steegborn, Clemens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504108/ https://www.ncbi.nlm.nih.gov/pubmed/23185430 http://dx.doi.org/10.1371/journal.pone.0049761 |
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