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Up-Regulation of leucocytes Genes Implicated in Telomere Dysfunction and Cellular Senescence Correlates with Depression and Anxiety Severity Scores

BACKGROUND: Major depressive disorder (MDD) is frequently associated with chronic medical illness responsible of increased disability and mortality. Inflammation and oxidative stress are considered to be the major mediators of the allostatic load, and has been shown to correlate with telomere erosio...

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Detalles Bibliográficos
Autores principales: Teyssier, Jean-Raymond, Chauvet-Gelinier, Jean-Christophe, Ragot, Sylviane, Bonin, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504145/
https://www.ncbi.nlm.nih.gov/pubmed/23185405
http://dx.doi.org/10.1371/journal.pone.0049677