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OCT4 Positively Regulates Survivin Expression to Promote Cancer Cell Proliferation and Leads to Poor Prognosis in Esophageal Squamous Cell Carcinoma

BACKGROUND: OCT4 and Survivin are important factors for cancer cell proliferation, renewal and dedifferentiation, and correlate with resistance to radiotherapy and chemotherapy in most human cancers, but their regulatory mechanisms are not well known. METHODOLOGY/PRINCIPAL FINDINGS: In this study, 5...

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Detalles Bibliográficos
Autores principales: Li, Chunguang, Yan, Yan, Ji, Weidan, Bao, Longlong, Qian, Haihua, Chen, Lei, Wu, Mengchao, Chen, Hezhong, Li, Zhigang, Su, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504152/
https://www.ncbi.nlm.nih.gov/pubmed/23185410
http://dx.doi.org/10.1371/journal.pone.0049693