Cargando…

OCT4 Positively Regulates Survivin Expression to Promote Cancer Cell Proliferation and Leads to Poor Prognosis in Esophageal Squamous Cell Carcinoma

BACKGROUND: OCT4 and Survivin are important factors for cancer cell proliferation, renewal and dedifferentiation, and correlate with resistance to radiotherapy and chemotherapy in most human cancers, but their regulatory mechanisms are not well known. METHODOLOGY/PRINCIPAL FINDINGS: In this study, 5...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Chunguang, Yan, Yan, Ji, Weidan, Bao, Longlong, Qian, Haihua, Chen, Lei, Wu, Mengchao, Chen, Hezhong, Li, Zhigang, Su, Changqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504152/ https://www.ncbi.nlm.nih.gov/pubmed/23185410 http://dx.doi.org/10.1371/journal.pone.0049693

Ejemplares similares

Clinicopathological and Prognostic Significance of Survivin Over-Expression in Patients with Esophageal Squamous Cell Carcinoma: A Meta-Analysis
por: Li, Chunguang, et al.
Publicado: (2012)

Transcriptional factor OCT4 promotes esophageal cancer metastasis by inducing epithelial-mesenchymal transition through VEGF-C/VEGFR-3 signaling pathway
por: Li, Chunguang, et al.
Publicado: (2017)

OCT4 increases BIRC5 and CCND1 expression and promotes cancer progression in hepatocellular carcinoma
por: Cao, Lu, et al.
Publicado: (2013)

Oncolytic adenovirus-mediated dual knockdown of survivin and OCT4 improves therapeutic efficacy in esophageal cancer
por: Li, Chunguang, et al.
Publicado: (2023)

Expression of SIRT1 and survivin correlates with poor prognosis in esophageal squamous cell carcinoma
por: Yan, Li, et al.
Publicado: (2020)

Prognostic value of association of OCT4 with LEF1 expression in esophageal squamous cell carcinoma and their impact on epithelial‐mesenchymal transition, invasion, and migration
por: Zhao, Yue, et al.
Publicado: (2018)

Removal of tumor thrombus from the azygos vein in an esophageal squamous cell carcinoma patient
por: Lu, Qijue, et al.
Publicado: (2020)

Co-expression of VEGF-C and survivin predicts poor prognosis in esophageal squamous cell carcinoma
por: Zeng, Yun-Zhu, et al.
Publicado: (2021)

Expression and Prognostic Value of Id-4 in Patients with Esophageal Squamous Cell Carcinoma
por: Wang, Xinyu, et al.
Publicado: (2020)

Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma
por: Hui, Marco K. C., et al.
Publicado: (2012)

The transcription factor LEF1 promotes tumorigenicity and activates the TGF-β signaling pathway in esophageal squamous cell carcinoma
por: Zhao, Yue, et al.
Publicado: (2019)

SOX12 contributes to the activation of the JAK2/STAT3 pathway and malignant transformation of esophageal squamous cell carcinoma
por: Li, Chunguang, et al.
Publicado: (2021)

LEF1/Id3/HRAS axis promotes the tumorigenesis and progression of esophageal squamous cell carcinoma
por: Wang, Xinyu, et al.
Publicado: (2020)

Hypoxic Tumor-Derived Exosomal Circ0048117 Facilitates M2 Macrophage Polarization Acting as miR-140 Sponge in Esophageal Squamous Cell Carcinoma
por: Lu, Qijue, et al.
Publicado: (2020)

Stem‐Cell Therapy for Esophageal Anastomotic Leakage by Autografting Stromal Cells in Fibrin Scaffold
por: Xue, Xiang, et al.
Publicado: (2019)

High expression of survivin predicts poor prognosis in cervical squamous cell carcinoma treated with paclitaxel and carboplatin
por: Zhang, Yunzhong, et al.
Publicado: (2019)

Construction a new nomogram prognostic model for predicting overall survival after radical resection of esophageal squamous cancer
por: Shi, Bowen, et al.
Publicado: (2023)

Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy
por: Wang, Weiguo, et al.
Publicado: (2013)

PRMT1 regulates the tumour-initiating properties of esophageal squamous cell carcinoma through histone H4 arginine methylation coupled with transcriptional activation
por: Zhao, Yue, et al.
Publicado: (2019)

MiR-34a-5p Inhibits Proliferation, Migration, Invasion and Epithelial-mesenchymal Transition in Esophageal Squamous Cell Carcinoma by Targeting LEF1 and Inactivation of the Hippo-YAP1/TAZ Signaling Pathway
por: Wang, Xinyu, et al.
Publicado: (2020)

Use of exosome transcriptome-based analysis to identify novel biomarkers in patients with locally advanced esophageal squamous cell carcinoma undergoing neoadjuvant chemoradiotherapy
por: Yang, Yang, et al.
Publicado: (2023)

Survivin expression in oral squamous cell carcinoma
por: Muzio, L Lo, et al.
Publicado: (2003)

Protein phosphatase PHLPP induces cell apoptosis and exerts anticancer activity by inhibiting Survivin phosphorylation and nuclear export in gallbladder cancer
por: Qiu, Yinghe, et al.
Publicado: (2015)

Multicenter, single-arm, phase II trial of camrelizumab and chemotherapy as neoadjuvant treatment for locally advanced esophageal squamous cell carcinoma
por: Liu, Jun, et al.
Publicado: (2022)

LncRNA NLIPMT Inhibits Tumorigenesis in Esophageal Squamous-Cell Carcinomas by Regulating miR-320/Survivin Axis
por: Li, Demao, et al.
Publicado: (2020)

Growth inhibition and chemo-radiosensitization of esophageal squamous cell carcinoma by survivin-shRNA lentivirus transfection
por: Zhou, Changlin, et al.
Publicado: (2018)

Survivin Regulates Bad Gene Expression by Binding to Its Promoter and Modulates Cell Cycle and Apoptosis in Esophageal Carcinoma Cell
por: Chen, Yan, et al.
Publicado: (2021)

Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal model
por: Xu, Gaoya, et al.
Publicado: (2014)

High expression of HSP60 and survivin predicts poor prognosis for oral squamous cell carcinoma patients
por: Zhou, Ying, et al.
Publicado: (2023)

High expression of PDGFA predicts poor prognosis of esophageal squamous cell carcinoma
por: Han, Na, et al.
Publicado: (2021)

Survivin-Based Treatment Strategies for Squamous Cell Carcinoma
por: Santarelli, Andrea, et al.
Publicado: (2018)

Down‐regulation of POTEG predicts poor prognosis in esophageal squamous cell carcinoma patients
por: Wang, Ling, et al.
Publicado: (2018)

Phosphorylated AKT1 is associated with poor prognosis in esophageal squamous cell carcinoma
por: Zhu, Zhengfei, et al.
Publicado: (2015)

The influence of thoracic duct ligation on long-term survival of patients with esophageal cancer: a propensity score-matched analysis
por: Fei, Xiang, et al.
Publicado: (2020)

DEPTOR suppresses the progression of esophageal squamous cell carcinoma and predicts poor prognosis
por: Ji, Yan-Mei, et al.
Publicado: (2016)

A novel prognostic mRNA/miRNA signature for esophageal cancer and its immune landscape in cancer progression
por: Zhao, Yue, et al.
Publicado: (2021)

Upregulation of METTL3 Expression Predicts Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma
por: Xia, Tian-Liang, et al.
Publicado: (2020)

Stratified treatment of localized cervical esophageal squamous cell carcinoma induced by neoadjuvant immunotherapy plus chemotherapy (SCENIC)
por: Li, Chunguang, et al.
Publicado: (2022)

Hypertension predicts a poor prognosis in patients with esophageal squamous cell carcinoma
por: Liang, Jie, et al.
Publicado: (2018)

Genetic polymorphisms of NAMPT related with susceptibility to esophageal Squamous cell carcinoma
por: Zhang, Chuanzhen, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dop7vtbr79p79ovn0sr4ao812j