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UVB-induced COX-2 expression requires histone H3 phosphorylation at Ser10 and Ser28

Cyclooxygenase-2 (COX-2) is an inducible enzyme that contributes to the generation of chronic inflammation in response to chemical carcinogens and environmental stresses, including ultraviolet B (UVB) irradiation. Although post-translational histone modifications are believed to play an important ro...

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Detalles Bibliográficos
Autores principales: Keum, Young-Sam, Kim, Hong-Gyum, Bode, Ann M., Surh, Young-Joon, Dong, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504182/
https://www.ncbi.nlm.nih.gov/pubmed/22391560
http://dx.doi.org/10.1038/onc.2012.71