Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations

Rett syndrome (RTT) is a neurodevelopmental autism spectrum disorder caused by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. Here, we describe the first characterization and neuronal differentiation of induced pluripotent stem (iPS) cells derived from Mecp2-deficient mice. Fully reprog...

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Detalles Bibliográficos
Autores principales: Farra, N, Zhang, W-B, Pasceri, P, Eubanks, J H, Salter, M W, Ellis, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504383/
https://www.ncbi.nlm.nih.gov/pubmed/22230884
http://dx.doi.org/10.1038/mp.2011.180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504383/
https://www.ncbi.nlm.nih.gov/pubmed/22230884
http://dx.doi.org/10.1038/mp.2011.180

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