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Sterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob Mice

Obesity and its metabolic complications are associated with increased expression/activity of stearoyl-CoA desaturase-1 (SCD1), a major regulator of lipid metabolism. Reduction or ablation of this enzyme is associated with an improved metabolic profile and has gained attention as a target for pharmac...

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Detalles Bibliográficos
Autores principales: Ortinau, Laura C., Pickering, R. Taylor, Nickelson, Karen J., Stromsdorfer, Kelly L., Naik, Chaitasi Y., Haynes, Rebecca A., Bauman, Dale E., Rector, R. Scott, Fritsche, Kevin L., Perfield, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504409/
https://www.ncbi.nlm.nih.gov/pubmed/23209931
http://dx.doi.org/10.5402/2012/947323