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Sterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob Mice
Obesity and its metabolic complications are associated with increased expression/activity of stearoyl-CoA desaturase-1 (SCD1), a major regulator of lipid metabolism. Reduction or ablation of this enzyme is associated with an improved metabolic profile and has gained attention as a target for pharmac...
Autores principales: | Ortinau, Laura C., Pickering, R. Taylor, Nickelson, Karen J., Stromsdorfer, Kelly L., Naik, Chaitasi Y., Haynes, Rebecca A., Bauman, Dale E., Rector, R. Scott, Fritsche, Kevin L., Perfield, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504409/ https://www.ncbi.nlm.nih.gov/pubmed/23209931 http://dx.doi.org/10.5402/2012/947323 |
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