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Oleic Acid Induces Lung Injury in Mice through Activation of the ERK Pathway

Oleic acid (OA) can induce acute lung injury in experimental models. In the present work, we used intratracheal OA injection to show augmented oedema formation, cell migration and activation, lipid mediator, and cytokine productions in the bronchoalveolar fluids of Swiss Webster mice. We also demons...

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Detalles Bibliográficos
Autores principales: Gonçalves-de-Albuquerque, Cassiano Felippe, Silva, Adriana Ribeiro, Burth, Patrícia, de Moraes, Isabel Matos Medeiros, Oliveira, Flora Magno de Jesus, Younes-Ibrahim, Mauricio, dos Santos, Maria da Conceição Batista, D'Ávila, Heloísa, Bozza, Patrícia Torres, Faria Neto, Hugo Caire de Castro, de Castro Faria, Mauro Velho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504460/
https://www.ncbi.nlm.nih.gov/pubmed/23209347
http://dx.doi.org/10.1155/2012/956509