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Physical activity and environmental enrichment regulate the generation of neural precursors in the adult mouse substantia nigra in a dopamine-dependent manner

BACKGROUND: Parkinson’s disease is characterized by a continuous loss of neurons within the substantia nigra (SN) leading to a depletion of dopamine. Within the adult SN as a non-neurogenic region, cells with mainly oligodendrocytic precursor characteristics, expressing the neuro-glial antigen-2 (NG...

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Detalles Bibliográficos
Autores principales: Klaissle, Philipp, Lesemann, Anne, Huehnchen, Petra, Hermann, Andreas, Storch, Alexander, Steiner, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504527/
https://www.ncbi.nlm.nih.gov/pubmed/23110504
http://dx.doi.org/10.1186/1471-2202-13-132