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VEGF directly suppresses activation of T cells from ascites secondary to ovarian cancer via VEGF receptor type 2
BACKGROUND: Vascular endothelial growth factor action in tumour angiogenesis is well characterised; nevertheless, it functions as a key element in the promotion of the immune system’s evasion by tumours. We sought to investigate the possible direct effect of VEGF on T-cell activation and through whi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504940/ https://www.ncbi.nlm.nih.gov/pubmed/23169339 http://dx.doi.org/10.1038/bjc.2012.468 |