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Network enrichment analysis: extension of gene-set enrichment analysis to gene networks

BACKGROUND: Gene-set enrichment analyses (GEA or GSEA) are commonly used for biological characterization of an experimental gene-set. This is done by finding known functional categories, such as pathways or Gene Ontology terms, that are over-represented in the experimental set; the assessment is bas...

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Detalles Bibliográficos
Autores principales: Alexeyenko, Andrey, Lee, Woojoo, Pernemalm, Maria, Guegan, Justin, Dessen, Philippe, Lazar, Vladimir, Lehtiö, Janne, Pawitan, Yudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505158/
https://www.ncbi.nlm.nih.gov/pubmed/22966941
http://dx.doi.org/10.1186/1471-2105-13-226