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Molecular mechanism implicated in Pemetrexed-induced apoptosis in human melanoma cells

BACKGROUND: Metastatic melanoma is a lethal skin cancer and its incidence is rising every year. It represents a challenge for oncologist, as the current treatment options are non-curative in the majority of cases; therefore, the effort to find and/or develop novel compounds is mandatory. Pemetrexed...

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Detalles Bibliográficos
Autores principales: Buqué, Aitziber, Muhialdin, Jangi Sh, Muñoz, Alberto, Calvo, Begoña, Carrera, Sergio, Aresti, Unai, Sancho, Aintzane, Rubio, Itziar, López-Vivanco, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505171/
https://www.ncbi.nlm.nih.gov/pubmed/22537194
http://dx.doi.org/10.1186/1476-4598-11-25