Evaluation of the immune responses induced by four targeted DNA vaccines encoding the juvenile liver fluke antigen, cathepsin B in a mouse model

BACKGROUND: Liver fluke can infect cattle and sheep, and is also emerging as a human pathogen in developing countries. Cathepsin B (Cat B2) is a major cysteine protease secreted by the juvenile flukes. To enhance the immune responses of Cat B2, the cDNA sequence was fused with four different DNA vac...

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Detalles Bibliográficos
Autores principales: Jayaraj, Rama, Piedrafita, David, Spithill, Terry, Smooker, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505173/
https://www.ncbi.nlm.nih.gov/pubmed/22938392
http://dx.doi.org/10.1186/1479-0556-10-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505173/
https://www.ncbi.nlm.nih.gov/pubmed/22938392
http://dx.doi.org/10.1186/1479-0556-10-7

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