Cargando…

LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types

BACKGROUND: The relative contribution of epigenetic mechanisms to carcinogenesis is not well understood, including the extent to which epigenetic dysregulation and somatic mutations target similar genes and pathways. We hypothesize that during carcinogenesis, certain pathways or biological gene sets...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jung H, Karnovsky, Alla, Mahavisno, Vasudeva, Weymouth, Terry, Pande, Manjusha, Dolinoy, Dana C, Rozek, Laura S, Sartor, Maureen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505188/
https://www.ncbi.nlm.nih.gov/pubmed/23033966
http://dx.doi.org/10.1186/1471-2164-13-526