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LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types
BACKGROUND: The relative contribution of epigenetic mechanisms to carcinogenesis is not well understood, including the extent to which epigenetic dysregulation and somatic mutations target similar genes and pathways. We hypothesize that during carcinogenesis, certain pathways or biological gene sets...
Autores principales: | Kim, Jung H, Karnovsky, Alla, Mahavisno, Vasudeva, Weymouth, Terry, Pande, Manjusha, Dolinoy, Dana C, Rozek, Laura S, Sartor, Maureen A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505188/ https://www.ncbi.nlm.nih.gov/pubmed/23033966 http://dx.doi.org/10.1186/1471-2164-13-526 |
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