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A Single-Dose Study of Denosumab in Patients With Various Degrees of Renal Impairment

This 16-week study evaluated pharmacokinetics and pharmacodynamics of denosumab in 55 subjects with renal function ranging from normal to dialysis-dependent kidney failure. Participants received a single 60-mg subcutaneous dose of denosumab. Kidney function groups were based on calculations using th...

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Detalles Bibliográficos
Autores principales: Block, Geoffrey A, Bone, Henry G, Fang, Liang, Lee, Edward, Padhi, Desmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505375/
https://www.ncbi.nlm.nih.gov/pubmed/22461041
http://dx.doi.org/10.1002/jbmr.1613