ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum

BACKGROUND: Knowledge of the rate of action of compounds against cultured malaria parasites is required to determine the optimal time-points for drug mode of action studies, as well as to predict likely in vivo parasite clearance rates in order to select optimal hit compounds for further development...

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Detalles Bibliográficos
Autores principales: Khan, Tasmiyah, van Brummelen, Anna C, Parkinson, Christopher J, Hoppe, Heinrich C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505462/
https://www.ncbi.nlm.nih.gov/pubmed/23134617
http://dx.doi.org/10.1186/1475-2875-11-369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505462/
https://www.ncbi.nlm.nih.gov/pubmed/23134617
http://dx.doi.org/10.1186/1475-2875-11-369

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