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ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum
BACKGROUND: Knowledge of the rate of action of compounds against cultured malaria parasites is required to determine the optimal time-points for drug mode of action studies, as well as to predict likely in vivo parasite clearance rates in order to select optimal hit compounds for further development...
Autores principales: | Khan, Tasmiyah, van Brummelen, Anna C, Parkinson, Christopher J, Hoppe, Heinrich C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505462/ https://www.ncbi.nlm.nih.gov/pubmed/23134617 http://dx.doi.org/10.1186/1475-2875-11-369 |
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