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Increased afterload induces pathological cardiac hypertrophy: a new in vitro model

Increased afterload results in ‘pathological’ cardiac hypertrophy, the most important risk factor for the development of heart failure. Current in vitro models fall short in deciphering the mechanisms of hypertrophy induced by afterload enhancement. The aim of this study was to develop an experiment...

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Detalles Bibliográficos
Autores principales: Hirt, Marc N., Sörensen, Nils A., Bartholdt, Lena M., Boeddinghaus, Jasper, Schaaf, Sebastian, Eder, Alexandra, Vollert, Ingra, Stöhr, Andrea, Schulze, Thomas, Witten, Anika, Stoll, Monika, Hansen, Arne, Eschenhagen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505530/
https://www.ncbi.nlm.nih.gov/pubmed/23099820
http://dx.doi.org/10.1007/s00395-012-0307-z