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Combination Therapy with Losartan and Pioglitazone Additively Reduces Renal Oxidative and Nitrative Stress Induced by Chronic High Fat, Sucrose, and Sodium Intake

We recently showed that combination therapy with losartan and pioglitazone provided synergistic effects compared with monotherapy in improving lesions of renal structure and function in Sprague-Dawley rats fed with a high-fat, high-sodium diet and 20% sucrose solution. This study was designed to exp...

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Detalles Bibliográficos
Autores principales: Kong, Xiang, Zhang, Yan, Wu, Hai-bing, Li, Fang-xia, Zhang, Dao-you, Su, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505666/
https://www.ncbi.nlm.nih.gov/pubmed/23213350
http://dx.doi.org/10.1155/2012/856085