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Interleukin-17 and Interleukin-22 Induced Proinflammatory Cytokine Production in Keratinocytes via Inhibitor of Nuclear Factor κB Kinase-α Expression

BACKGROUND: The pathogenesis of psoriasis may involve the interleukin (IL)-23 and Th17-mediated immune responses. Th17 cells secret IL-17 and IL-22, which mediates dermal inflammation and acanthosis. OBJECTIVE: As inhibitor of nuclear factor κB kinase-α (IKKα) has been previously identified as a pri...

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Detalles Bibliográficos
Autores principales: Cho, Kyung-Ah, Kim, Jin-Young, Woo, So-Youn, Park, Hyun Jeong, Lee, Kyung Ho, Pae, Chi-Un
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505769/
https://www.ncbi.nlm.nih.gov/pubmed/23197904
http://dx.doi.org/10.5021/ad.2012.24.4.398