Influence of Methylenetetrahydrofolate Reductase C677T, A1298C, and G80A Polymorphisms on the Survival of Pediatric Patients with Acute Lymphoblastic Leukemia

The influence of genic polymorphisms involved in metabolism of chemotherapeutic agents as the methotrexate (MTX) has been studied mainly in acute lymphoblastic leukemia (ALL) of childhood. Advances in treatment may be attributed to identification of prognostic factors added to chemotherapy protocol....

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Detalles Bibliográficos
Autores principales: de Deus, Dayse Maria Vasconcelos, de Lima, Elker Lene Santos, Seabra Silva, Rafaela Maria, Leite, Edinalva Pereira, Cartaxo Muniz, Maria Tereza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505921/
https://www.ncbi.nlm.nih.gov/pubmed/23198157
http://dx.doi.org/10.1155/2012/292043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505921/
https://www.ncbi.nlm.nih.gov/pubmed/23198157
http://dx.doi.org/10.1155/2012/292043

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