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Influence of Methylenetetrahydrofolate Reductase C677T, A1298C, and G80A Polymorphisms on the Survival of Pediatric Patients with Acute Lymphoblastic Leukemia
The influence of genic polymorphisms involved in metabolism of chemotherapeutic agents as the methotrexate (MTX) has been studied mainly in acute lymphoblastic leukemia (ALL) of childhood. Advances in treatment may be attributed to identification of prognostic factors added to chemotherapy protocol....
Autores principales: | de Deus, Dayse Maria Vasconcelos, de Lima, Elker Lene Santos, Seabra Silva, Rafaela Maria, Leite, Edinalva Pereira, Cartaxo Muniz, Maria Tereza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505921/ https://www.ncbi.nlm.nih.gov/pubmed/23198157 http://dx.doi.org/10.1155/2012/292043 |
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