The Interface between BCR-ABL-Dependent and -Independent Resistance Signaling Pathways in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a clonal hematopoietic disorder characterized by the presence of the Philadelphia chromosome which resulted from the reciprocal translocation between chromosomes 9 and 22. The pathogenesis of CML involves the constitutive activation of the BCR-ABL tyrosine kinase, w...

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Detalles Bibliográficos
Autores principales: Nestal de Moraes, Gabriela, Souza, Paloma Silva, Costas, Fernanda Casal de Faria, Vasconcelos, Flavia Cunha, Reis, Flaviana Ruade Souza, Maia, Raquel Ciuvalschi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505928/
https://www.ncbi.nlm.nih.gov/pubmed/23259070
http://dx.doi.org/10.1155/2012/671702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505928/
https://www.ncbi.nlm.nih.gov/pubmed/23259070
http://dx.doi.org/10.1155/2012/671702

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