A dual switch controls bacterial enhancer-dependent transcription

Bacterial RNA polymerases (RNAPs) are targets for antibiotics. Myxopyronin binds to the RNAP switch regions to block structural rearrangements needed for formation of open promoter complexes. Bacterial RNAPs containing the major variant σ(54) factor are activated by enhancer-binding proteins (bEBPs)...

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Detalles Bibliográficos
Autores principales: Wiesler, Simone C., Burrows, Patricia C., Buck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505966/
https://www.ncbi.nlm.nih.gov/pubmed/22965125
http://dx.doi.org/10.1093/nar/gks844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505966/
https://www.ncbi.nlm.nih.gov/pubmed/22965125
http://dx.doi.org/10.1093/nar/gks844

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