Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

Prion diseases are transmissible neurodegenerative disorders affecting both humans and animals. The cellular prion protein, PrP(C), and the abnormal infectious form, PrP(Sc), are found associated with exosomes, which are small 50–130 nm vesicles released from cells. Exosomes also contain microRNAs (...

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Detalles Bibliográficos
Autores principales: Bellingham, Shayne A., Coleman, Bradley M., Hill, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505968/
https://www.ncbi.nlm.nih.gov/pubmed/22965126
http://dx.doi.org/10.1093/nar/gks832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505968/
https://www.ncbi.nlm.nih.gov/pubmed/22965126
http://dx.doi.org/10.1093/nar/gks832

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