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Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses
Therapeutic gene transfer by replication-defective viral vectors or, for cancer treatment, by replication-competent oncolytic viruses shows high promise for treatment of major diseases. To ensure safety, timing or dosing in patients, external control of therapeutic gene expression is desirable or ev...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505972/ https://www.ncbi.nlm.nih.gov/pubmed/22885302 http://dx.doi.org/10.1093/nar/gks734 |