Inducible and reversible regulation of endogenous gene in mouse

Methods for generating loss-of-function mutations, such as conventional or conditional gene knockout, are widely used in deciphering gene function in vivo. By contrast, inducible and reversible regulation of endogenous gene expression has not been well established. Using a mouse model, we demonstrat...

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Detalles Bibliográficos
Autores principales: Sun, Ruilin, Zhao, Kai, Shen, Ruling, Cai, Lei, Yang, Xingyu, Kuang, Ying, Mao, Jifang, Huang, Fang, Wang, Zhugang, Fei, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505985/
https://www.ncbi.nlm.nih.gov/pubmed/22879379
http://dx.doi.org/10.1093/nar/gks738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505985/
https://www.ncbi.nlm.nih.gov/pubmed/22879379
http://dx.doi.org/10.1093/nar/gks738

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