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Cellular and cytokine-dependent immunosuppressive mechanisms of grm1-transgenic murine melanoma

Grm1-transgenic mice spontaneously develop cutaneous melanoma. This model allowed us to scrutinize the generic immune responses over the course of melanoma development. To this end, lymphocytes obtained from spleens, unrelated lymph nodes and tumor-draining lymph nodes of mice with no evidence of di...

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Detalles Bibliográficos
Autores principales: Alb, Miriam, Sie, Christopher, Adam, Christian, Chen, Suzie, Becker, Jürgen C., Schrama, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506202/
https://www.ncbi.nlm.nih.gov/pubmed/22674057
http://dx.doi.org/10.1007/s00262-012-1290-9