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The potential for selective pharmacological therapies through biased receptor signaling
The discovery that not all agonists uniformly activate cellular signaling pathways (biased signaling) has greatly changed the drug discovery process for agonists and the strategy for treatment of disease with agonists. Technological advances have enabled complex receptor behaviors to be viewed indep...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506267/ https://www.ncbi.nlm.nih.gov/pubmed/22947056 http://dx.doi.org/10.1186/2050-6511-13-3 |