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Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points
BACKGROUND: Two commercially available microneedle rollers with a needle length of 200 μm and 300 μm were selected to examine the influence of microneedle pretreatment on the percutaneous permeation of four non-steroidal anti-inflammatory drugs (diclofenac, ibuprofen, ketoprofen, paracetamol) with d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506268/ https://www.ncbi.nlm.nih.gov/pubmed/22947102 http://dx.doi.org/10.1186/2050-6511-13-5 |