Gremlin in the pathogenesis of hepatocellular carcinoma complicating chronic hepatitis C: an immunohistochemical and PCR study of human liver biopsies

BACKGROUND: The possible role of secretory products of fibrous tissue in the development of hepatocellular carcinoma (HCC) complicating chronic hepatitis C was investigated. Our hypothesis was that gremlin, secreted by fibroblasts, inhibited bone morphogenic protein (BMP), which mediates stem cell m...

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Detalles Bibliográficos
Autores principales: Guimei, Maha, Baddour, Nahed, ElKaffash, Dalal, Abdou, Laila, Taher, Yousry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506438/
https://www.ncbi.nlm.nih.gov/pubmed/22839096
http://dx.doi.org/10.1186/1756-0500-5-390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506438/
https://www.ncbi.nlm.nih.gov/pubmed/22839096
http://dx.doi.org/10.1186/1756-0500-5-390

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