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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells
BACKGROUND: Huntington’s Disease (HD) is a devastating neurodegenerative disorder that clinically manifests as motor dysfunction, cognitive impairment and psychiatric symptoms. There is currently no cure for this progressive and fatal disorder. The causative mutation of this hereditary disease is a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506453/ https://www.ncbi.nlm.nih.gov/pubmed/22613578 http://dx.doi.org/10.1186/1756-6606-5-17 |