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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells

BACKGROUND: Huntington’s Disease (HD) is a devastating neurodegenerative disorder that clinically manifests as motor dysfunction, cognitive impairment and psychiatric symptoms. There is currently no cure for this progressive and fatal disorder. The causative mutation of this hereditary disease is a...

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Detalles Bibliográficos
Autores principales:	Juopperi, Tarja A, Kim, Woon Ryoung, Chiang, Cheng-Hsuan, Yu, Huimei, Margolis, Russell L, Ross, Christopher A, Ming, Guo-li, Song, Hongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506453/ https://www.ncbi.nlm.nih.gov/pubmed/22613578 http://dx.doi.org/10.1186/1756-6606-5-17

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