Cargando…

Myotubularin family phosphatase ceMTM3 is required for muscle maintenance by preventing excessive autophagy in Caenorhabditis elegans

BACKGROUND: Autophagy is a ubiquitous cellular process responsible for the bulk degradation of cytoplasmic components through the autophagosomal-lysosomal pathway. In skeletal muscle, autophagy has been regarded as a key regulator for muscle mass maintenance, and its imbalance leads to sarcopenia. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Xiaokun, Ma, Junfeng, Lin, Feng, Zhao, Wanke, Fu, Xueqi, Zhao, Zhizhuang Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506462/
https://www.ncbi.nlm.nih.gov/pubmed/23114011
http://dx.doi.org/10.1186/1471-2121-13-28