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Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization

BACKGROUND: Promotion of endothelial normalization restores tumor oxygenation and obstructs tumor cells invasion, intravasation, and metastasis. We therefore investigated whether a vasoactive drug, tanshinone IIA, could inhibit metastasis by inducing vascular normalization after palliative resection...

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Detalles Bibliográficos
Autores principales: Wang, Wen-Quan, Liu, Liang, Sun, Hui-Chuan, Fu, Yan-Ling, Xu, Hua-Xiang, Chai, Zong-Tao, Zhang, Qiang-Bo, Kong, Ling-Qun, Zhu, Xiao-Dong, Lu, Lu, Ren, Zheng-Gang, Tang, Zhao-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506473/
https://www.ncbi.nlm.nih.gov/pubmed/23137165
http://dx.doi.org/10.1186/1756-8722-5-69