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Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization
BACKGROUND: Promotion of endothelial normalization restores tumor oxygenation and obstructs tumor cells invasion, intravasation, and metastasis. We therefore investigated whether a vasoactive drug, tanshinone IIA, could inhibit metastasis by inducing vascular normalization after palliative resection...
Autores principales: | Wang, Wen-Quan, Liu, Liang, Sun, Hui-Chuan, Fu, Yan-Ling, Xu, Hua-Xiang, Chai, Zong-Tao, Zhang, Qiang-Bo, Kong, Ling-Qun, Zhu, Xiao-Dong, Lu, Lu, Ren, Zheng-Gang, Tang, Zhao-You |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506473/ https://www.ncbi.nlm.nih.gov/pubmed/23137165 http://dx.doi.org/10.1186/1756-8722-5-69 |
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