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Cul4B regulates neural progenitor cell growth

BACKGROUND: Cullin ubiquitin ligases are activated via the covalent modification of Cullins by the small ubiquitin-like protein nedd8 in a process called neddylation. Genetic mutations of cullin-4b (cul4b) cause a prevalent type of X-linked intellectual disability (XLID) in males, but the physiologi...

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Detalles Bibliográficos
Autores principales: Liu, Helio C, Enikolopov, Grigori, Chen, Yuzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506489/
https://www.ncbi.nlm.nih.gov/pubmed/22992378
http://dx.doi.org/10.1186/1471-2202-13-112