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Cul4B regulates neural progenitor cell growth
BACKGROUND: Cullin ubiquitin ligases are activated via the covalent modification of Cullins by the small ubiquitin-like protein nedd8 in a process called neddylation. Genetic mutations of cullin-4b (cul4b) cause a prevalent type of X-linked intellectual disability (XLID) in males, but the physiologi...
Autores principales: | Liu, Helio C, Enikolopov, Grigori, Chen, Yuzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506489/ https://www.ncbi.nlm.nih.gov/pubmed/22992378 http://dx.doi.org/10.1186/1471-2202-13-112 |
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