Novel Functions of the Phosphatase SHP2 in the DNA Replication and Damage Checkpoints

Replication stress- and DNA damage-induced cell cycle checkpoints are critical for maintaining genome stability. To identify protein phosphatases involved in the activation and maintenance of the checkpoints, we have carried out RNA interference-based screens with a human phosphatome shRNA library....

Descripción completa

Detalles Bibliográficos
Autores principales: Tsang, Yiu Huen, Han, Xianxian, Man, Wing Yu, Lee, Nelson, Poon, Randy Y. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506573/
https://www.ncbi.nlm.nih.gov/pubmed/23189174
http://dx.doi.org/10.1371/journal.pone.0049943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506573/
https://www.ncbi.nlm.nih.gov/pubmed/23189174
http://dx.doi.org/10.1371/journal.pone.0049943

Ejemplares similares