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Novel Functions of the Phosphatase SHP2 in the DNA Replication and Damage Checkpoints
Replication stress- and DNA damage-induced cell cycle checkpoints are critical for maintaining genome stability. To identify protein phosphatases involved in the activation and maintenance of the checkpoints, we have carried out RNA interference-based screens with a human phosphatome shRNA library....
Autores principales: | Tsang, Yiu Huen, Han, Xianxian, Man, Wing Yu, Lee, Nelson, Poon, Randy Y. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506573/ https://www.ncbi.nlm.nih.gov/pubmed/23189174 http://dx.doi.org/10.1371/journal.pone.0049943 |
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