Learning from Decoys to Improve the Sensitivity and Specificity of Proteomics Database Search Results

The statistical validation of database search results is a complex issue in bottom-up proteomics. The correct and incorrect peptide spectrum match (PSM) scores overlap significantly, making an accurate assessment of true peptide matches challenging. Since the complete separation between the true and...

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Detalles Bibliográficos
Autores principales: Yadav, Amit Kumar, Kumar, Dhirendra, Dash, Debasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506577/
https://www.ncbi.nlm.nih.gov/pubmed/23189209
http://dx.doi.org/10.1371/journal.pone.0050651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506577/
https://www.ncbi.nlm.nih.gov/pubmed/23189209
http://dx.doi.org/10.1371/journal.pone.0050651

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