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Burn Injury Triggered Dysfunction in Dendritic Cell Response to TLR9 Activation and Resulted in Skewed T Cell Functions

Severe trauma such as burn injury is often associated with a systemic inflammatory syndrome characterized by a hyperactive innate immune response and suppressed adaptive immune function. Dendritic cells (DCs), which sense pathogens via their Toll-like receptors (TLRs), play a pivotal role in protect...

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Detalles Bibliográficos
Autores principales: Shen, Haitao, de Almeida, Patricia E., Kang, Kyung H., Yao, Pamela, Chan, Camie W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506591/
https://www.ncbi.nlm.nih.gov/pubmed/23189191
http://dx.doi.org/10.1371/journal.pone.0050238